I move back and forth between a lot of different keyboard layout. In some case it makes sense, especially for special characters (the position of " on the classic QWERTY irk me a lot).
But my general advise is : if you change, change to reduce the physical pain. Do not change to get faster or more efficient. The speed of typing is really not something important for a dev. My 2 cents.
I often tried to switch to Dvorak or Neo II, which I picked up pretty quickly each time. Even without ~r/[rd]elabeling/ my keyboard.
But I have to admit, it only worked out during long streaks of freetime. It really felt better and was more fun to type. But as soon as I had to sit at a foreign computer which had QWERTZ layout, I had to relearn that one, while unlearning Dvorak/Neo.
I tried to learn to keep at a good typing rate with both of them at the same time, but I wasn’t able to. I had to make a decission, and even if I liked Neo the most out of these three, I had to make the decision in favor of QWERTZ, just because I’m swapping computers as well as operating systems constantly. Most of them are provided as is and/or owned by customers.
So you really have to try if any of the alternative layouts fits your situation and environment. Also be aware of a massive drop in your typing performance during the training phase. And do not switch back to QWERTY just because its easier for this one email, especially not during training