I used to use it but I much prefer to use Phoenix.LiveView.JS commands and LiveVIew Hooks these days. I don’t find Alpine to be worth the hassle of having to deal with the compatability with LiveView or the additionaly bundle size.

You might be interested in this thread:
https://elixirforum.com/t/better-interop-with-javascript-libraries-react-svelte-etc/64041

For many apps with LiveView probably don’t need a “JS-side” as such (the JS module can do some basic stuff).

When LiveView doesn’t cut it and you do need JS, personally I’d recommend rendering frontend JS components here and there (most frameworks allow you to sprinkle components here and there on the page - the whole page doesn’t need to be an SPA).

My go-to would be Svelte - for that you could use LiveSvelte or you could use a library I recently published Komodo